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Hypoxia-inducible Factor-1-mediated Regulation of Semaphorin 4D Affects Tumor Growth and Vascularity

Tumor progression and metastasis depend on the ability of cancer cells to initiate angiogenesis to ensure delivery of oxygen, nutrients, and growth factors to tumor cells and provide access to the systemic circulation. Hypoxia-inducible factor-1 (HIF-1) can activate expression of a broad range of ge...

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Detalles Bibliográficos
Main Authors: Sun, Qiangming, Zhou, Hua, Binmadi, Nada O., Basile, John R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797277/
https://ncbi.nlm.nih.gov/pubmed/19762474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.057166
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