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Functional Expression of an Arachnid Sodium Channel Reveals Residues Responsible for Tetrodotoxin Resistance in Invertebrate Sodium Channels

Tetrodotoxin (TTX) is a potent blocker of voltage-gated sodium channels, but not all sodium channels are equally sensitive to inhibition by TTX. The molecular basis of differential TTX sensitivity of mammalian sodium channels has been largely elucidated. In contrast, our knowledge about the sensitiv...

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Bibliografische gegevens
Hoofdauteurs: Du, Yuzhe, Nomura, Yoshiko, Liu, Zhiqi, Huang, Zachary Y., Dong, Ke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797157/
https://ncbi.nlm.nih.gov/pubmed/19828457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.045690
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