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Plasma Levels of Transforming Growth Factor-β1 Reflect Left Ventricular Remodeling in Aortic Stenosis

BACKGROUND: TGF-β1 is involved in cardiac remodeling through an auto/paracrine mechanism. The contribution of TGF-β1 from plasmatic source to pressure overload myocardial remodeling has not been analyzed. We investigated, in patients with valvular aortic stenosis (AS), and in mice subjected to trans...

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Bibliografiska uppgifter
Huvudupphovsmän: Villar, Ana V., Cobo, Manuel, Llano, Miguel, Montalvo, Cecilia, González-Vílchez, Francisco, Martín-Durán, Rafael, Hurlé, María A., Nistal, J. Francisco
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797091/
https://ncbi.nlm.nih.gov/pubmed/20041033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008476
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