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Loss of Smyhc1 or Hsp90α1 Function Results in Different Effects on Myofibril Organization in Skeletal Muscles of Zebrafish Embryos

BACKGROUND: Myofibrillogenesis requires the correct folding and assembly of sarcomeric proteins into highly organized sarcomeres. Heat shock protein 90α1 (Hsp90α1) has been implicated as a myosin chaperone that plays a key role in myofibrillogenesis. Knockdown or mutation of hsp90α1 resulted in comp...

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Detalhes bibliográficos
Main Authors: Codina, Marta, Li, Junling, Gutiérrez, Joaquim, Kao, Joseph P. Y., Du, Shao Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797074/
https://ncbi.nlm.nih.gov/pubmed/20049323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008416
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