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Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes

BACKGROUND: Tumor-specific cytotoxic T cells and infiltrating lymphocytes are frequently found in tumor tissues in patients with nasopharyngeal carcinoma (NPC). Most patients with NPC, however, especially those with advanced stages, have a poor clinical prognosis despite conventional immunotherapy....

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Detalhes bibliográficos
Main Authors: Liu, Peng, Xie, Bai-Lu, Cai, Shao-Hui, He, Yun-Wen, Zhang, Ge, Yi, Yan-Mei, Du, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797021/
https://ncbi.nlm.nih.gov/pubmed/19948041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-416
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