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SIRT1 controls circadian clock circuitry and promotes cell survival: a connection with age-related neoplasms
Aging is believed to be a primary risk factor for cancer. Interestingly, the sirtuin family of class III histone deacetylases (HDACs) has been implicated in the regulation of longevity and may be a lost link between aging and cancer. SIRT1, a nicotinamide adenine dinucleotide (NAD(+))-dependent sirt...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Federation of American Societies for Experimental Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796903/ https://ncbi.nlm.nih.gov/pubmed/19439501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-129148 |
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