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SIRT1 controls circadian clock circuitry and promotes cell survival: a connection with age-related neoplasms

Aging is believed to be a primary risk factor for cancer. Interestingly, the sirtuin family of class III histone deacetylases (HDACs) has been implicated in the regulation of longevity and may be a lost link between aging and cancer. SIRT1, a nicotinamide adenine dinucleotide (NAD(+))-dependent sirt...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Jung-Hynes, Brittney, Ahmad, Nihal
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Federation of American Societies for Experimental Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796903/
https://ncbi.nlm.nih.gov/pubmed/19439501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-129148
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