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Significant contributions of the extraembryonic membranes and maternal genotype to the placental pathology in heterozygous Nsdhl deficient female embryos

Mutations in the gene encoding the cholesterol biosynthetic enzyme NSDHL are associated with the X-linked male-lethal bare patches (Bpa) mouse. Mutant male embryos for several Nsdhl alleles die in midgestation with placental insufficiency. We examined here a possible role of the maternal genotype in...

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Detalhes bibliográficos
Main Authors: Cunningham, David, Talabere, Tiffany, Bir, Natalie, Kennedy, Matthew, McBride, Kim L., Herman, Gail E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796896/
https://ncbi.nlm.nih.gov/pubmed/19880419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp502
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