Maternal Infection with Trypanosoma cruzi and Congenital Chagas Disease Induce a Trend to a Type 1 Polarization of Infant Immune Responses to Vaccines

BACKGROUND: We previously showed that newborns congenitally infected with Trypanosoma cruzi (M+B+) display a strong type 1 parasite-specific T cell immune response, whereas uninfected newborns from T. cruzi-infected mothers (M+B−) are prone to produce higher levels of proinflammatory cytokines than...

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Bibliografiska uppgifter
Huvudupphovsmän: Dauby, Nicolas, Alonso-Vega, Cristina, Suarez, Eduardo, Flores, Amilcar, Hermann, Emmanuel, Córdova, Marisol, Tellez, Tatiana, Torrico, Faustino, Truyens, Carine, Carlier, Yves
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2009
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796860/
https://ncbi.nlm.nih.gov/pubmed/20041029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000571
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