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Avoiding the high Bonferroni penalty in genome-wide association studies
A major challenge in genome-wide association studies (GWASs) is to derive the multiple testing threshold when hypothesis tests are conducted using a large number of single nucleotide polymorphisms. Permutation tests are considered the gold standard in multiple testing adjustment in genetic associati...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796708/ https://ncbi.nlm.nih.gov/pubmed/19434714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20430 |
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