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Kinetic Simulation of a Centrifugal Bioreactor for High Population Density Hybridoma Culture
Demand for increasingly complex post-translationally modified proteins, such as monoclonal antibodies (mAbs), necessitates the use of mammalian hosts for production. The focus of this paper is a continuous centrifugal bioreactor (CCBR) capable of increasing volumetric productivity for mAb production...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796705/ https://ncbi.nlm.nih.gov/pubmed/19806634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.240 |
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