Transgenerational Effect of Fetal Programming on Vascular Phenotype and Reactivity in Nitric Oxide Knockout Mouse Model

OBJECTIVE: To investigate the transgenerational effect of fetal vascular programming METHODS: Homozygous NOS3 knockout and wild type controls (NOS3+/+WT) were cross-bred to obtain heterozygous offspring that developed in (KO−/−) mothers lacking a functional NOS3 (KOM) versus wild-type control mother...

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Autores principales: COSTANTINE, Maged M., GHULMIYYAH, Labib M., TAMAYO, Esther, HANKINS, Gary D.V, SAADE, George R., LONGO, Monica
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796619/
https://ncbi.nlm.nih.gov/pubmed/18771972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2008.07.002
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