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Phosphorylation-induced changes in backbone dynamics of the dematin headpiece C-terminal domain

Dematin is an actin-binding protein abundant in red blood cells and other tissues. It contains a villin-type `headpiece' F-actin-binding domain at its extreme C-terminus. The isolated dematin headpiece domain (DHP) undergoes a significant conformational change upon phosphorylation. The mutation...

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Detalhes bibliográficos
Main Authors: Vugmeyster, Liliya, McKnight, C. James
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796552/
https://ncbi.nlm.nih.gov/pubmed/19030997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-008-9289-4
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