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Cross-talk between membrane-initiated and nuclear-initiated oestrogen signaling in the hypothalamus
It is increasingly evident that 17β-oestradiol (E2) via a distinct membrane oestrogen receptor (Gq-mER) can rapidly activate kinase pathways to have multiple downstream actions in CNS neurons. We have found that E2 can rapidly reduce the potency of the GABA(B) receptor agonist baclofen and mu-opioid...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796511/ https://ncbi.nlm.nih.gov/pubmed/19187465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2826.2009.01846.x |
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