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Cross-talk between membrane-initiated and nuclear-initiated oestrogen signaling in the hypothalamus

It is increasingly evident that 17β-oestradiol (E2) via a distinct membrane oestrogen receptor (Gq-mER) can rapidly activate kinase pathways to have multiple downstream actions in CNS neurons. We have found that E2 can rapidly reduce the potency of the GABA(B) receptor agonist baclofen and mu-opioid...

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Sonraí Bibleagrafaíochta
Main Authors: Roepke, Troy A., Qiu, Jian, Bosch, Martha A., Rønnekleiv, Oline K., Kelly, Martin J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796511/
https://ncbi.nlm.nih.gov/pubmed/19187465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2826.2009.01846.x
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