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Nicotine Enhances the Antiapoptotic Function of Mcl-1 through Phosphorylation

Lung cancer has a strong etiological association with cigarette smoking. Nicotine, a major component in tobacco smoke, functions as a survival agonist that inhibits apoptosis following various stresses. However, the mechanism of action remains elusive. Mcl-1, a major antiapoptotic protein of the Bcl...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhao, Jinfeng, Xin, Meiguo, Wang, Ton, Zhang, Yangde, Deng, Xingming
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796280/
https://ncbi.nlm.nih.gov/pubmed/19903766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0304
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