Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics

Proteomic and lipidomic profiling was performed over a time course of acute hepatitis C virus (HCV) infection in cultured Huh-7.5 cells to gain new insights into the intracellular processes influenced by this virus. Our proteomic data suggest that HCV induces early perturbations in glycolysis, the p...

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Detalhes bibliográficos
Main Authors: Diamond, Deborah L., Syder, Andrew J., Jacobs, Jon M., Sorensen, Christina M., Walters, Kathie-Anne, Proll, Sean C., McDermott, Jason E., Gritsenko, Marina A., Zhang, Qibin, Zhao, Rui, Metz, Thomas O., Camp, David G., Waters, Katrina M., Smith, Richard D., Rice, Charles M., Katze, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796172/
https://ncbi.nlm.nih.gov/pubmed/20062526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000719
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