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[Ca(2+)](i) as a potential downregulator of α(2)β(1)-integrin-mediated A2058 tumor cell migration to type IV collagen
We have investigated cellular Ca(2+) regulation during A2058 human melanoma cell chemotaxis to type IV collagen (CIV). We have identified α(2)β(1)-integrin as the primary mediator of A2058 cell response to CIV in vitro. Integrin ligation initiated a characteristic intracellular Ca(2+) concentration...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2001
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796124/ https://ncbi.nlm.nih.gov/pubmed/11401832 |
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