Genetic deficiency of the alpha subunit of the guanine nucleotide-binding protein Gs as the molecular basis for Albright hereditary osteodystrophy.

Patients who have pseudohypoparathyroidism type I associated with Albright hereditary osteodystrophy commonly have a genetic deficiency of the alpha subunit of the G protein that stimulates adenylyl cyclase (alpha Gs) (ATP pyrophosphate-lyase, EC 4.6.1.1). To discover the molecular mechanism that ca...

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Hauptverfasser: Levine, M A, Ahn, T G, Klupt, S F, Kaufman, K D, Smallwood, P M, Bourne, H R, Sullivan, K A, Van Dop, C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC279602/
https://ncbi.nlm.nih.gov/pubmed/2829196
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