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Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis.

A strong correlation was found between the basal levels of membrane-bound protein kinase C and the ability of B16 melanoma cell sublines (F10, F1, and BL6) to metastasize to the lung after intravenous injection. By treating with tumor-promoting phorbol esters for 1 hr, the low-metastasizing F1 cells...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Gopalakrishna, R, Barsky, S H
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1988
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279601/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3422445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.2.612
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