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Comparative analysis of different approaches for dealing with candidate regions in the context of a genome-wide association study

Genome-wide association studies (GWAS) test hundreds of thousands of single-nucleotide polymorphisms (SNPs) for association to a trait, treating each marker equally and ignoring prior evidence of association to specific regions. Typically, promising regions are selected for further investigation bas...

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Autors principals: Lantieri, Francesca, Jhun, Min A, Park, Jungsun, Park, Taesung, Devoto, Marcella
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795997/
https://ncbi.nlm.nih.gov/pubmed/20018090
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