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Phorbol esters induce multidrug resistance in human breast cancer cells.

Mechanisms responsible for broad-based resistance to antitumor drugs derived from natural products (multidrug resistance) are incompletely understood. Agents known to reverse the multidrug-resistant phenotype (verapamil and trifluoperazine) can also inhibit the activity of protein kinase C. When we...

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Detalhes bibliográficos
Main Authors: Fine, R L, Patel, J, Chabner, B A
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC279595/
https://ncbi.nlm.nih.gov/pubmed/3422442
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