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Haplotype association analysis of North American Rheumatoid Arthritis Consortium data using a generalized linear model with regularization

The Genetic Analysis Workshop 16 rheumatoid arthritis data include a set of 868 cases and 1194 controls genotyped at 545,080 single-nucleotide polymorphisms (SNPs) from the Illumina 550 k chip. We focus on investigating chromosomes 6 and 18, which have 35,574 and 16,450 SNPs, respectively. Associati...

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Bibliographic Details
Main Authors: Guo, Wei, Liang, Chin-yuan, Lin, Shili
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795930/
https://ncbi.nlm.nih.gov/pubmed/20018023
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