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Accommodating population stratification in case-control association analysis: a new test and its application to genome-wide study on rheumatoid arthritis

It is well known that conventional association tests can lead to excessive false positives when there is population stratification. We propose a new test for detecting genetic association with a case-control study design. Unlike some other methods for handling population stratification, we treat the...

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Autors principals: Zhang, Yufang, Xiao, Xiangjun, Wang, Kai
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795883/
https://ncbi.nlm.nih.gov/pubmed/20017976
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