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Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites

The avian IgY antibody isotype shares a common ancestor with both mammalian IgG and IgE and so provides a means to study the evolution of their structural and functional specialisations. Although both IgG and IgE bind to their leukocyte Fc receptors with 1:1 stoichiometry, IgY binds to CHIR-AB1, a r...

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Detalhes bibliográficos
Main Authors: Taylor, Alexander I., Sutton, Brian J., Calvert, Rosaleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795851/
https://ncbi.nlm.nih.gov/pubmed/19733585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dci.2009.08.012
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