Disulfide bonds and thermal stability in T4 lysozyme.

Disulfide bonds are thought to serve a stabilizing role in extracellular globular proteins, but little is known about the modes of stabilization or their mechanisms. Thermodynamic data presented here demonstrate that an engineered 3-97 disulfide bond previously shown to stabilize T4 lysozyme in vitr...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Wetzel, R, Perry, L J, Baase, W A, Becktel, W J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279556/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3277175/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.2.401
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