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Reconstruction of the yeast Snf1 kinase regulatory network reveals its role as a global energy regulator

Highly conserved among eukaryotic cells, the AMP-activated kinase (AMPK) is a central regulator of carbon metabolism. To map the complete network of interactions around AMPK in yeast (Snf1) and to evaluate the role of its regulatory subunit Snf4, we measured global mRNA, protein and metabolite level...

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Detalhes bibliográficos
Main Authors: Usaite, Renata, Jewett, Michael C, Oliveira, Ana Paula, Yates, John R, Olsson, Lisbeth, Nielsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795470/
https://ncbi.nlm.nih.gov/pubmed/19888214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.67
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