Novel Infectivity-Enhanced Oncolytic Adenovirus with a Capsid-Incorporated Dual-Imaging Moiety for Monitoring Virotherapy in Ovarian Cancer

We sought to develop a cancer-targeted, infectivity-enhanced oncolytic adenovirus that embodies a capsid-labeling fusion for noninvasive dual-modality imaging of ovarian cancer virotherapy. A functional fusion protein composed of fluorescent and nuclear imaging tags was genetically incorporated into...

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Bibliographic Details
Main Authors: Kimball, Kristopher J., Rivera, Angel A., Zinn, Kurt R., Icyuz, Mert, Saini, Vaibhav, Li, Jing, Zhu, Zeng B., Siegal, Gene P., Douglas, Joanne T., Curiel, David T., Alvarez, Ronald D., Borovjagin, Anton V.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795397/
https://ncbi.nlm.nih.gov/pubmed/19796604
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