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Directed differentiation of hippocampal stem/progenitor cells in the adult brain

Adult neurogenesis is a lifelong feature of brain plasticity; however, the potency of adult neural stem/progenitor cells in vivo remains unclear. We found that retrovirus-mediated overexpression of a single gene, the bHLH transcription factor Ascl1, redirected the fate of the proliferating adult hip...

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Detalhes bibliográficos
Principais autores: Jessberger, Sebastian, Toni, Nicolas, Clemenson, Gregory D, Ray, Jasodhara, Gage, Fred H
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795354/
https://ncbi.nlm.nih.gov/pubmed/18587391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2148
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