Nutrient Availability as a Mechanism for Selection of Antibiotic Tolerant Pseudomonas aeruginosa within the CF Airway

Microbes are subjected to selective pressures during chronic infections of host tissues. Pseudomonas aeruginosa isolates with inactivating mutations in the transcriptional regulator LasR are frequently selected within the airways of people with cystic fibrosis (CF), and infection with these isolates...

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Bibliographische Detailangaben
Hauptverfasser: Hoffman, Lucas R., Richardson, Anthony R., Houston, Laura S., Kulasekara, Hemantha D., Martens-Habbena, Willm, Klausen, Mikkel, Burns, Jane L., Stahl, David A., Hassett, Daniel J., Fang, Ferric C., Miller, Samuel I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795201/
https://ncbi.nlm.nih.gov/pubmed/20072604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000712
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