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Molecular dynamics simulations reveal that AEDANS is an inert fluorescent probe for the study of membrane proteins

Computer simulations were carried out of a number of AEDANS-labeled single cysteine mutants of a small reference membrane protein, M13 major coat protein, covering 60% of its primary sequence. M13 major coat protein is a single membrane-spanning, α-helical membrane protein with a relatively large wa...

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Bibliographic Details
Main Authors: Vos, Werner L., Schor, Marieke, Baumgaertner, Artur, Tieleman, D. Peter, Hemminga, Marcus A.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795155/
https://ncbi.nlm.nih.gov/pubmed/19669748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-009-0527-9
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