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Base substitutions, frameshifts, and small deletions constitute ionizing radiation-induced point mutations in mammalian cells.

The relative role of point mutations and large genomic rearrangements in ionizing radiation-induced mutagenesis has been an issue of long-standing interest. Recent studies using Southern blotting analysis permit the partitioning of ionizing radiation-induced mutagenesis in mammalian cells into detec...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Grosovsky, A J, de Boer, J G, de Jong, P J, Drobetsky, E A, Glickman, B W
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1988
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279508/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3422416/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.1.185
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