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Nonrandom distribution of structural mutants in ethylnitrosourea-treated cultured human lymphoblastoid cells.

Two-dimensional polyacrylamide gel electrophoresis has been used to detect somatic cell gene mutations altering protein structure, following ethylnitrosourea treatment of cultured human lymphoblastoid cells. A total of 267 polypeptides encoded by 263 loci were scored in a series of 1143 lymphoblasto...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hanash, S M, Boehnke, M, Chu, E H, Neel, J V, Kuick, R D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279504/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3422414/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.1.165
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