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Recent Patents on Novel P2X(7) Receptor Antagonists and Their Potential for Reducing Central Nervous System Inflammation

Inflammation arises in the CNS from a number of neurodegenerative and oncogenic disorders, as well as from ischemic and traumatic brain injuries. These pathologies give rise to increased levels of extracellular adenine nucleotides which, via activation of a variety of cell surface P2 purinergic rece...

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Detalhes bibliográficos
Main Authors: Friedle, Scott A., Curet, Marjorie A., Watters, Jyoti J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794961/
https://ncbi.nlm.nih.gov/pubmed/19705995
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