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Potentiometric Detection of DNA Hybridization using Enzyme-Induced Metallization and a Silver Ion Selective Electrode

Here we report on a highly sensitive potentiometric detection of DNA hybridization. The new assay uses a low-volume solid-contact silver ion-selective electrode (Ag(+)-ISE) to monitor the depletion of silver ions induced by the biocatalytic reaction of the alkaline-phosphatase enzyme tag. The result...

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Main Authors: Wu, Jie, Chumbimuni-Torres, Karin Y., Galik, Michal, Thammakhet, Chongdee, Haake, David A., Wang, Joseph
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794934/
https://ncbi.nlm.nih.gov/pubmed/19908886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac9018507
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