A Cell-penetrating Peptide Derived from Human Lactoferrin with Conformation-dependent Uptake Efficiency

The molecular events that contribute to the cellular uptake of cell-penetrating peptides (CPP) are still a matter of intense research. Here, we report on the identification and characterization of a 22-amino acid CPP derived from the human milk protein, lactoferrin. The peptide exhibits a conformati...

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Detalhes bibliográficos
Main Authors: Duchardt, Falk, Ruttekolk, Ivo R., Verdurmen, Wouter P. R., Lortat-Jacob, Hugues, Bürck, Jochen, Hufnagel, Hansjörg, Fischer, Rainer, van den Heuvel, Maaike, Löwik, Dennis W. P. M., Vuister, Geerten W., Ulrich, Anne, de Waard, Michel, Brock, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794725/
https://ncbi.nlm.nih.gov/pubmed/19858187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.036426
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