Native genomic blotting: high-resolution mapping of DNase I-hypersensitive sites and protein-DNA interactions.
DNase I-hypersensitive sites are observed in the promoter regions of actively expressed genes, potentially active genes, and genes that were once active. We have developed an approach that greatly increases the resolution for mapping these sites by electrophoresing genomic DNA on native polyacrylami...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1988
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3422413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.1.16 |
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