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New metabolites of fenofibrate in Sprague–Dawley rats by UPLC-ESI-QTOF-MS-based metabolomics coupled with LC-MS/MS

1. Fenofibrate has been widely used for the treatment of dyslipidaemia with a long history. Species differences of its metabolism were reported, but its metabolites in rodent have not been fully investigated. 2. Urine and plasma samples were collected before and after oral dosages of fenofibrate in...

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Autors principals: Liu, A., Chen, Y., Yang, Z., Feng, Y., Rui, W., Luo, W., Liu, Y., Gonzalez, F. J., Dai, R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794380/
https://ncbi.nlm.nih.gov/pubmed/19350456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498250802680827
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