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Understanding Gene Sequence Variation in the Context of Transcription Regulation in Yeast
DNA sequence polymorphism in a regulatory protein can have a widespread transcriptional effect. Here we present a computational approach for analyzing modules of genes with a common regulation that are affected by specific DNA polymorphisms. We identify such regulatory-linkage modules by integrating...
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Auteurs principaux: | , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Public Library of Science
2010
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794365/ https://ncbi.nlm.nih.gov/pubmed/20066030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000800 |
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