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Understanding Gene Sequence Variation in the Context of Transcription Regulation in Yeast

DNA sequence polymorphism in a regulatory protein can have a widespread transcriptional effect. Here we present a computational approach for analyzing modules of genes with a common regulation that are affected by specific DNA polymorphisms. We identify such regulatory-linkage modules by integrating...

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Détails bibliographiques
Auteurs principaux: Gat-Viks, Irit, Meller, Renana, Kupiec, Martin, Shamir, Ron
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794365/
https://ncbi.nlm.nih.gov/pubmed/20066030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000800
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