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Postnatal Survival of Mice with Maternal Duplication of Distal Chromosome 7 Induced by a Igf2/H19 Imprinting Control Region Lacking Insulator Function

The misexpressed imprinted genes causing developmental failure of mouse parthenogenones are poorly defined. To obtain further insight, we investigated misexpressions that could cause the pronounced growth deficiency and death of fetuses with maternal duplication of distal chromosome (Chr) 7 (MatDup....

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Autors principals: Han, Li, Szabó, Piroska E., Mann, Jeffrey R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794364/
https://ncbi.nlm.nih.gov/pubmed/20062522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000803
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