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Decreased Expression of the Voltage-Dependent Anion Channel in Differentiated PC-12 and SH-SY5Y Cells Following Low-Level Pb Exposure

Lead (Pb) has been shown to disrupt cellular energy metabolism, which may underlie the learning deficits and cognitive dysfunctions associated with environmental Pb exposure. The voltage-dependent anion channel (VDAC) plays a central role in regulating energy metabolism in neurons by maintaining cel...

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Bibliografske podrobnosti
Main Authors: Prins, John M., Park, Sunyoung, Lurie, Diana I.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794334/
https://ncbi.nlm.nih.gov/pubmed/19822599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp249
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