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Functional features of gene expression profiles differentiating gastrointestinal stromal tumours according to KIT mutations and expression

BACKGROUND: Gastrointestinal stromal tumours (GISTs) represent a heterogeneous group of tumours of mesenchymal origin characterized by gain-of-function mutations in KIT or PDGFRA of the type III receptor tyrosine kinase family. Although mutations in either receptor are thought to drive an early onco...

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Détails bibliographiques
Auteurs principaux: Ostrowski, Jerzy, Polkowski, Marcin, Paziewska, Agnieszka, Skrzypczak, Magdalena, Goryca, Krzysztof, Rubel, Tymon, Kokoszyñska, Katarzyna, Rutkowski, Piotr, Nowecki, Zbigniew I, Dobosz, Anna Jerzak Vel, Jarosz, Dorota, Ruka, Wlodzimierz, Wyrwicz, Lucjan S
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794290/
https://ncbi.nlm.nih.gov/pubmed/19943934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-413
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