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Full-length apolipoprotein E protects against the neurotoxicity of an apoE-related peptide
Apolipoprotein E was found to protect against the neurotoxic effects of a dimeric peptide derived from the receptor-binding region of this protein (residues 141–149). Both apoE3 and apoE4 conferred protection but the major N-terminal fragment of each isoform did not. Nor was significant protection p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794278/ https://ncbi.nlm.nih.gov/pubmed/19836363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.10.021 |
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