Combining Laser Microsurgery and Finite Element Modeling to Assess Cell-Level Epithelial Mechanics

Laser microsurgery and finite element modeling are used to determine the cell-level mechanics of the amnioserosa—a morphogenetically crucial epithelium on the dorsal surface of fruit fly embryos (Drosophila melanogaster). In the experiments, a tightly focused laser ablates a subcellular hole (1 μm i...

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Bibliografiske detaljer
Main Authors: Hutson, M. Shane, Veldhuis, J., Ma, Xiaoyan, Lynch, Holley E., Cranston, P. Graham, Brodland, G. Wayne
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2009
Fag:
Biophysical Systems and Multicellular Dynamics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793361/
https://ncbi.nlm.nih.gov/pubmed/20006944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.034
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