Binding the Atypical RA Domain of Ste50p to the Unfolded Opy2p Cytoplasmic Tail Is Essential for the High-Osmolarity Glycerol Pathway

Activation of the high-osmolarity glycerol (HOG) pathway for osmoregulation in the yeast Saccharomyces cerevisiae involves interaction of the adaptor Ste50p with the cytoplasmic tail of single-transmembrane protein Opy2p. We have determined the solution structure of the Ste50p-RA (Ras association) d...

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Main Authors: Ekiel, Irena, Sulea, Traian, Jansen, Gregor, Kowalik, Maria, Minailiuc, Ovidiu, Cheng, Jing, Harcus, Doreen, Cygler, Miroslaw, Whiteway, Malcolm, Wu, Cunle
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793289/
https://ncbi.nlm.nih.gov/pubmed/19846660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-07-0645
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