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Oxidative Stress Inhibits Nuclear Protein Export by Multiple Mechanisms That Target FG Nucleoporins and Crm1

Nuclear transport of macromolecules is regulated by the physiological state of the cell and thus sensitive to stress. To define the molecular mechanisms that control nuclear export upon stress, cells were exposed to nonlethal concentrations of the oxidant diethyl maleate (DEM). These stress conditio...

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Detalhes bibliográficos
Main Authors: Crampton, Noah, Kodiha, Mohamed, Shrivastava, Sanhita, Umar, Rehan, Stochaj, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793288/
https://ncbi.nlm.nih.gov/pubmed/19828735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-05-0397
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