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Requirements for Recruitment of a G Protein-coupled Receptor to Clathrin-coated Pits in Budding Yeast

Endocytic internalization of G protein-coupled receptors (GPCRs) plays a critical role in down-regulation of GPCR signaling. The yeast mating pheromone receptor Ste2p has been used as a model to investigate mechanisms of signal transduction, modification, and endocytic internalization of GPCRs. We p...

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Autores principales: Toshima, Junko Y., Nakanishi, Jun-ichi, Mizuno, Kensaku, Toshima, Jiro, Drubin, David G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793282/
https://ncbi.nlm.nih.gov/pubmed/19828733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-07-0541
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