Differential enhancement of breast cancer cell motility and metastasis by helical and kinase domain mutations of class IA PI3K

Class IA (p85/p110) PI 3-kinases play a major role in regulating cell growth, survival, and motility. Activating mutations in the p110α isoform of the class IA catalytic subunit (PIK3CA) are commonly found in human cancers. These mutations lead to increased proliferation and transformation in cultur...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pang, Huan, Flinn, Rory, Patsialou, Antonia, Wyckoff, Jeffrey, Roussos, Evanthia T., Wu, Haiyan, Pozzutto, Maria, Goswami, Sumanta, Condeelis, John S., Bresnick, Anne R., Segall, Jeffrey E., Backer, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793177/
https://ncbi.nlm.nih.gov/pubmed/19903845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1968
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados