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High Throughput Sequencing and Proteomics to Identify Immunogenic Proteins of a New Pathogen: The Dirty Genome Approach

BACKGROUND: With the availability of new generation sequencing technologies, bacterial genome projects have undergone a major boost. Still, chromosome completion needs a costly and time-consuming gap closure, especially when containing highly repetitive elements. However, incomplete genome data may...

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Autori principali: Greub, Gilbert, Kebbi-Beghdadi, Carole, Bertelli, Claire, Collyn, François, Riederer, Beat M., Yersin, Camille, Croxatto, Antony, Raoult, Didier
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793016/
https://ncbi.nlm.nih.gov/pubmed/20037647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008423
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