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Use of Bacterially Expressed dsRNA to Downregulate Entamoeba histolytica Gene Expression

BACKGROUND: Modern RNA interference (RNAi) methodologies using small interfering RNA (siRNA) oligonucleotide duplexes or episomally synthesized hairpin RNA are valuable tools for the analysis of gene function in the protozoan parasite Entamoeba histolytica. However, these approaches still require ti...

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Autors principals: Solis, Carlos F., Santi-Rocca, Julien, Perdomo, Doranda, Weber, Christian, Guillén, Nancy
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793006/
https://ncbi.nlm.nih.gov/pubmed/20037645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008424
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