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Fructose-2,6-Bisphosphate Is Lower in Copper Deficient Rat Cerebellum Despite Higher Content of Phosphorylated AMP-Activated Protein Kinase

Limitation in copper (Cu) leads to pathophysiology in developing brain. Cu deficiency impairs brain mitochondria and results in high brain lactate suggesting augmented anaerobic glycolysis. AMP activated protein kinase (AMPK) is a cellular energy “master-switch” that is thought to augment glycolysis...

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Detalhes bibliográficos
Main Authors: Gybina, Anna A., Prohaska, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792878/
https://ncbi.nlm.nih.gov/pubmed/18703756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3181/0804-RM-132
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