Blunted frequency-dependent upregulation of cardiac output is related to impaired relaxation in diastolic heart failure

AIMS: We tested the hypothesis that, in heart failure with normal ejection fraction (HFNEF), diastolic dysfunction is accentuated at increasing heart rates, and this contributes to impaired frequency-dependent augmentation of cardiac output. METHODS AND RESULTS: In 17 patients with HFNEF (median age...

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Main Authors: Wachter, Rolf, Schmidt-Schweda, Stephan, Westermann, Dirk, Post, Heiner, Edelmann, Frank, Kasner, Mario, Lüers, Claus, Steendijk, Paul, Hasenfuß, Gerd, Tschöpe, Carsten, Pieske, Burkert
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Clinical Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792717/
https://ncbi.nlm.nih.gov/pubmed/19720638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehp341
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